Experience in Incorporating Dynamic Perfusion in an Established Deceased Donor Renal Transplant Program.

Abstract

Study Approach: In our institution, 757 kidney transplants have been performed, the Deceased Donor being the most frequent. Hence the interest in comparing kidney preservation techniques and their effects on the future conditions of the recipient.

Objective: To evaluate the results and early evolution of the transplanted kidney, using dynamic perfusion as a new technology during the procurement and incorporating it into an already established program.

Materials and Methods: THIS IS A DESCRIPTIVE STUDY OF A SERIES OF CASES AND AN ANALYTICAL COMPARISON.

This is a 2:1 sequential comparative study to analyze the difference between patients transplanted with a conventional hypothermic static preservation kidney and patients transplanted with a continuous mobile perfusion system.

Discussion: LifePort® provides a sealed, sterile environment where a specially formulated saline solution is gently pumped through the kidney at low temperatures to minimize tissue damage while preserving the organ outside the body, allows organ perfusion and temperature recording , flow velocity, vascular resistance and pressure.

Results: 45% of the organs in static cold ischemia required hemodialysis compared to patients in continuous perfusion required hemodialysis in 30%.

Conclusions: The risk of delayed function and the need for dialysis in the immediate postoperative period are minimized.