Prostate adenocarcinoma as an incidental finding in radical cystoprostatectomy
DOI:
https://doi.org/10.54212/27068048.v8i1.31Keywords:
Radical cystoprostatectomy, synchronous tumor, prostate adenocarcinoma.Abstract
Objective: To present a clinical case of prostate adenocarcinoma as an incidental finding in radical cystoprostatectomy
Background: Radical cystoprostatectomy represents the most effective treatment for non-metastasic invasive muscle bladder cancer, multiple authors have documented prostate cancer in patients with bladder cancer, however it has been considered of little relevance in this regard. In a French multicenter study, an incidence ranging from 14 to 60% is reported, being more frequent at older age and confined to the gland.
Materials and Methods: We present a case of prostate adenocarcinoma Gleason 8 (4+4) in a 70 year old patient, as an incidental finding in the histopathological report after radical cystoprostatectomy
Results: Surgery and histopathological reptor confirms the diagnosis.
Conclusions: The incidental finding of a synchronous tumor is variable, its clinical signigicance has not yet been defined, however, it is considered that patients undergoing radical cystoprostatectom shoudl be previously studied to rule out prostatic pathology. If the histopathological finding is positive, it should be included in your post-surgical follow-up and the biochemical recurrence should be evaluated.
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Stein, J. Skinner, D. Radical cystectomy for invasive bladder cancer: long-term results of a standar procedure. World J Urol 2006;24:296-304 https://doi.org/10.1007/s00345-006-0061-7 DOI: https://doi.org/10.1007/s00345-006-0061-7
Babjuck M. Oosterlink W. et. Al. EAU Guidelines on non-invasive urotelial carcinoma of the bladder the 2020 update. Eur Urol. 2020:19-69
Majeed, A. Babb, P. et. Al. Trends in prostate cancer incidence, mortality survival in England and Wales 1971-1998. BJU Int 2000;85:1058-62. https://doi.org/10.1046/j.1464-410x.2000.00661.x DOI: https://doi.org/10.1046/j.1464-410x.2000.00661.x
Ruffion, A. Massoud, w. et. Al. PReservation of prostate during radical cystectomy . evaluation of prevalence of prostate cancer associated with bladder cancer Urology 2005;65:703-7. https://doi.org/10.1016/j.urology.2004.10.076 DOI: https://doi.org/10.1016/j.urology.2004.10.076
Dammiano, R. Di Lorenzo, G. et. Al. Clinicopathologic features of prostate adenocarcinoma incidentally discovered at the time of radical cystectomy . An evidence-based analiysis. European Urology 2007;52:648-657. https://doi.org/10.1016/j.eururo.2007.06.016 DOI: https://doi.org/10.1016/j.eururo.2007.06.016
Singh A. Jones, R. et. Al. Expression of p53 and pRb in bladder and prostate cancer in patients having both cancers. Anticancer Res 1999;19:5415-7.
Andoulakakis P, Schneider H. et. Al. Coincident vesical transitional cell carcinoma and prostatic carcinoma; clinical features and treatment. Br J Urol 1986;58:153-6. https://doi.org/10.1111/j.1464-410X.1986.tb09016.x DOI: https://doi.org/10.1111/j.1464-410X.1986.tb09016.x
Pignot, G. Salomon, L. et. Al. Clinicopathological characteristics of incidental prostate cancer discovered forn radical cystoprostatectomy specimen: a multicenter french study. Ann Surg Oncol 2014;21:684-690. https://doi.org/10.1245/s10434-013-3340-8 DOI: https://doi.org/10.1245/s10434-013-3340-8
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Copyright (c) 2020 Peter Mauricio Rojas Schippers , Erick Stanley Petersen Juárez
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