Urethroplasty with Oral Mucosa Grafts in Stages
DOI:
https://doi.org/10.54212/27068048.v9i1.16Keywords:
urethral stricture, complications, urethroplasty in stagesAbstract
Introduction: Urethral stricture is one of the main causes of obstructive symptoms in men with significant impact on their lives because of its multiple complications. Urethroplasty with oral mucosa grafts in stages has become a therapeutic option for complex anterior urethral stricture. Objective: To describe the results of urethroplasty with oral mucosa grafts in stages for complex anterior urethral stricture. Methodology: A descriptive, retrospective study of 12 male patients with complex anterior urethral stricture was carried out in the Service of Urology at the “Hermanos Ameijeiras” Hospital of Cuba, between 2016 and 2020. Results: The average age of the series was 41.7 years. Previous history of hypospadias, pendulum-bulbar location and stricture between 6.1 and 7 cm prevailed. 91.6% had more than one previous failed treatment, and severe urethral stenosis (7.8). Re-stenosis prevailed (33.3%) which was resolved in two patients, 83.3% successfully. A high percentage of the patients reported that their quality of life was improved as well as being satisfied with the results of the surgery when the second stage was completed. Conclusions: Urethroplasty with oral mucosa grafts in two stages is a therapeutic option to be considered for complex anterior urethral stricture given its satisfactory results
Downloads
References
Smith TG, 3rd. Current management of urethral stricture disease. Indian J Urol. 2016;32(1):27-33. https://doi.org/10.4103/0970-1591.173108 DOI: https://doi.org/10.4103/0970-1591.173108
Palomeque Martínez M CPG, Navarro Cutiño M. Uretroplastia con mucosa prepucial en la estrechez uretral. Rev Cub Urol. 2018; Volumen 7.
Verla W, Oosterlinck W, Spinoit A-F, y cols. A Comprehensive review emphasizing anatomy, etiology, diagnosis, and treatment of male urethral stricture disease. Biomed Res Int. 2019. 9046430. https://doi.org/10.1155/2019/9046430 DOI: https://doi.org/10.1155/2019/9046430
Kałużny A, Krukowski J, Matuszewski M. Erectile dysfunction after urethroplasty. Cent European J Urol. 2019; 72(4):402-7. https://doi.org/10.5173/ceju.2019.1737 DOI: https://doi.org/10.5173/ceju.2019.1737
Perdzyński W, Adamek M. Calibration of urethra with anti-scar gel as a new preventive method for stricture recurrence after urethroplasty performed due to refractory anterior urethral stricture disease. Cent European J Urol. 2020;73(1):80-90.
Soave A, Kluth L, Dahlem R, y cols. Outcome of buccal mucosa graft urethroplasty: a detailed analysis of success, morbidity and quality of life in a contemporary patient cohort at a referral center. BMC Urol. 2019; 19: 18. https://doi.org/10.1186/s12894-019-0449-5 DOI: https://doi.org/10.1186/s12894-019-0449-5
Selim M, Salem S, Elsherif E, y cols. Outcome of staged buccal mucosal graft for repair of long segment anterior urethral stricture. BMC Urol. 2019; 19:38. https://doi.org/10.1186/s12894-019-0466-4
Gallo Rolanía F, S MA. Uretroplastias con cirugía en dos tiempos y uretrostomias perineales. Arch Esp Urol. 2011; 64 (10): 939-944.
General Assembly of the World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. J Am Coll Dent. 2014 Summer; 81(3):14-8.
Nnabugwu II, Onuh AC, Anyimba SK, y cols. Comparing complications of urethral stricture across various ages: a retrospective analysis of findings from retrograde urethrogram and voiding cysto-urethrogram over 10 years. BMC Med Imaging. 2019; 19(84). https://doi.org/10.1186/s12880-019-0384-7 DOI: https://doi.org/10.1186/s12880-019-0384-7
Joshi P, Barbagli G, Batra V, y cols. A novel composite two-stage urethroplasty for complex penile strictures: A multicenter experience. Indian Journal of Urology. 2017; 33 (2): 155–158. https://doi.org/10.4103/0970-1591.203426 DOI: https://doi.org/10.4103/0970-1591.203426
Şimşek A, Yenice MG, Şeker KG, y cols. Evaluation of the results of dorsolateral buccal mucosal augmentation urethroplasty. Turk J Urol. 2018; 45(3): 223–229. https://doi.org/10.5152/tud.2018.47827 DOI: https://doi.org/10.5152/tud.2018.47827
Wilson SC, Stranix JT, Khurana K, y cols. Fasciocutaneous flap reinforcement of ventral onlay buccal mucosa grafts enables neophallus revision urethroplasty. Ther Adv Urol. 2016; 8(6): 331–337. https://doi.org/10.1177/1756287216673959 DOI: https://doi.org/10.1177/1756287216673959
Pedro IE. Resultados de la uretroplastia con mucosa bucal en el tratamiento de la estrechez uretral bulbar. Rev Cub Urol. 2018; Volumen 7.
Prabha V, Devaraju S, Vernekar R, y cols. Single stage: dorsolateral onlay buccal mucosal urethroplasty for long anterior urethral strictures using perineal route. Int Braz J Urol. 2016; 42(3): 564–570. https://doi.org/10.1590/S1677-5538.IBJU.2015.0184 DOI: https://doi.org/10.1590/S1677-5538.IBJU.2015.0184
Selim M, Salem S, Elsherif E, y cols. Outcome of staged buccal mucosal graft for repair of long segment anterior urethral stricture. BMC Urol. 2019; 19(1):38. https://doi.org/10.1186/s12894-019-0466-4 DOI: https://doi.org/10.1186/s12894-019-0466-4
Alsagheer GA, Fathi A, Abdel-Kader MS, y cols. Management of long segment anterior urethral stricture (≥ 8cm) using buccal mucosal (BM) graft and penile skin (PS) flap: outcome and predictors of failure. Int Braz J Urol. 2018; 44(1): 163–171. https://doi.org/10.1590/s1677-5538.ibju.2017.0083 DOI: https://doi.org/10.1590/s1677-5538.ibju.2017.0083
Spilotros M, Sihra N, Malde S, y cols. Buccal mucosal graft urethroplasty in men-risk factors for recurrence and complications: a third referral centre experience in anterior urethroplasty using buccal mucosal graft. Transl Androl Urol. 2017 11-2019; 6(3):510-516. https://doi.org/10.21037/tau.2017.03.69 DOI: https://doi.org/10.21037/tau.2017.03.69
Sukumar S, Elliott SP, Myers JB, y cols. Multi-Institutional Outcomes of Endoscopic Management of Stricture Recurrence after Bulbar Urethroplasty. J Urol. 2018; 200(4):837-842. https://doi.org/10.1016/j.juro.2018.04.081 DOI: https://doi.org/10.1016/j.juro.2018.04.081
Jasionowska S, Brunckhorst O, Rees RW, y cols. Redo-urethroplasty for the management of recurrent urethral strictures in males: a systematic review. World J Urol. 2019; 37(9):1801-1815. https://doi.org/10.1007/s00345-019-02709-7 DOI: https://doi.org/10.1007/s00345-019-02709-7
Saavedra AA, Rourke KF. Characterization and outcomes of urethroplasty for hypospadias-associated urethral strictures in adults. Can Urol Assoc J. 2019; 13(11): E335-E40. https://doi.org/10.5489/cuaj.5863 DOI: https://doi.org/10.5489/cuaj.5863
Campos-Juanatey F, Bugeja S, Dragova M, y cols. Single-stage tubular urethral reconstruction using oral grafts is an alternative to classical staged approach for selected penile urethral strictures. Asian J Androl. 2020; 22(2):134-139. https://doi.org/10.4103/aja.aja_78_19 DOI: https://doi.org/10.4103/aja.aja_78_19
Hoy NY, Chapman DW, Rourke KF. Better defining the optimal management of penile urethral strictures: A retrospective comparison of single-stage vs. two-stage urethroplasty. Can Urol Assoc J. 2019; 13(12):414-418. https://doi.org/10.5489/cuaj.5895 DOI: https://doi.org/10.5489/cuaj.5895
Ofoha CG, Ramyil VM, Dakum NK, y cols. Predictors of urethral stricture recurrence following urethroplasty: a retrospective review at the Jos University Teaching Hospital, Nigeria. Pan Afr Med J. 2019;32: 190. https://doi.org/10.11604/pamj.2019.32.190.18504 DOI: https://doi.org/10.11604/pamj.2019.32.190.18504
Lucas ET, Koff WJ, Rosito TE, y cols. Assessment of satisfaction and Quality of Life using self -reported questionnaires after urethroplasty: a prospective analysis. Int Braz J Urol. 2017; 43(2): 304-310. https://doi.org/10.1590/s1677-5538.ibju.2016.0207 DOI: https://doi.org/10.1590/s1677-5538.ibju.2016.0207
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Jenny María Rodríguez Cabrera & Isis Emérita Pedro Silva
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4.0 that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.